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Eden series CHO CD medium

Optimized CD media for high protein production in CHO cell culture

As early as 1998, BioEngine developed China's first serum-free medium for CHO cells. With a deep understanding of the key technologies and parameters of large-scale culture of CHO cells, BioEngine has continuously upgraded and optimized the medium formulation and manufacturing process. Based on rich project experience and an innovative iBioG-Med medium development platform, the first Eden CD CHO medium was launched in 2018 to promote high productivity in large-scale CHO cell culture. So far, Eden CD CHO media have been applied to 60+ clinical projects.

Eden series CHO CD medium

Features

Animal-derived component-free

Protein-free/Peptide ingredients-free

Chemically Defined

DMF Filing in Progress

Universality: Support the culture of various CHO cell lines (CHO-K1, CHO_ZN, Horizon, CHO-S, CHO DG44, etc.) in fed-batch, intensified fed-batch and perfusion modes

Advantages

Equivalent or superior performance to global brand products with better price and lead time;

4 advanced CMPM powder media production lines to meet different customer demand with high inter-batch consistency (CPK*>1.33);

Safe and compliant: chemically defined formulation minimizes the potential of contamination from animal-derived components and meets relevant compliance and regulatory requirements;

EU certified ISO13485:2016 QMS, all data are traceable;

Full documents support for IND application;

Strictly selected the "2 domestic+1 imported" raw material supplier model to to ensure a stable and reliable supply chain;

* CPK is a standard index to state the capability of one process. CPK=1.33: the process is capable and meets specification limits. The higher the CPK,the better.

Order Information
Basal Medium Feed Medium
Application
Product Name
Cat. No.
Size
Form Product Instruction (pdf) Inquiries /Sample application
CHO-K1, CHO-ZN, HORIZON, CHO-S, and CHO DG44, etc.
Eden B100S Basal Medium EXP0116401 200 L
Powder
Quick Message Inquiries /Sample application
EXP0116402 10 L
Powder
Eden B601S Basal Medium EXP0115601 200 L
Powder
EXP0115602 100 L
Powder
EXP0115603 10 L
Powder
Eden B600S Basal Medium
EXP0109901
10 L
Powder
EXP0109902
200 L
Powder
Eden B501S Basal Medium
EXP0106001
10 L
Powder
EXP0106002
200 L
Powder
Eden B401S Basal Medium
EXP0105901
10 L
Powder
EXP0105902
100 L
Powder
EXP0105903
200 L
Powder
Eden B300S Basal Medium
EXP0107901
100 L
Powder
EXP0107902
200 L
Powder
EXP0107903
10 L
Powder
Application
Product Name
Cat. No.
Size Form Product Instruction (pdf) Inquiries /Sample application
CHO-K1, CHO-ZN, HORIZON, CHO-S, and CHO DG44, etc.
Eden F100aS Feed Medium
EXP0116501
20 L
Powder
Quick Message Inquiries /Sample application
EXP0116502
1 L
Powder
Eden F602aS Feed Medium
EXP0115701
20 L
Powder
EXP0115702
1 L
Powder
Eden F601aS Feed Medium
EXP0112101
20 L
Powder
EXP0112102
10 L
Powder
EXP0112103
1 L
Powder
Eden F600aS Feed Medium
EXP0108901
20 L
Powder
EXP0108902
10 L
Powder
EXP0108903
1 L
Powder
Eden F500aS Feed Medium
EXP0105001
1 L
Powder
EXP0105002
20 L
Powder
Eden F400aS Feed Medium
EXP0104801
1 L
Powder
EXP0104802
20 L
Powder
Eden F100bS Feed Medium
EXP0116601
20 L
Powder
Quick Message
EXP0116602
1 L
Powder
Eden F600bS Feed Medium
EXP0108801
10 L
Powder
EXP0108802 1 L
Powder
Eden F200bS Feed Medium EXP0104601 1 L
Powder
EXP0104602 10 L
Powder
EXP0104603 20 L
Powder
EXP0104604 50 L
Powder
* DrivingM® is a registered trademark of Shanghai BioEngine Sci-Tech Co., Ltd.
Performance
Antibodies

In fed-batch mode, CHO cells cultured in Eden CD CHO media demonstrate higher viable cell density (VCD) and protein production than global brand A. Antibody titer of different CHO cell lines adapted in Eden CD CHO media reached 2-11 g/L.

In pulse perfusion mode, CHO cell cultures in Eden CD CHO media demonstrated superior performance than competitive global brands. When VVD=1.0, volumetric productivity (Vp) can reach up to 2.2 g/L/day, and the cumulative product expression in 14 days can reach 19 g/L, 55% higher than global brand B. When VVD=2.0, Vp can reach up to 3.3g/L/day, and the cumulative product expression in 14 days can reach 25 g/L.

Let us contact you

We have a professional technical team to provide high quality one-stop cell culture service from process development
and optimization, medium formulation design to medium processing and manufacturing for all biopharmaceutical companies.

If you have any question, please click "Quick Message" and leave your message, we will reply to you as soon as possible.
If anything urgent, please call (86)21-68582660-2792.

BioEngine

3F&4F, Building 3, Lane 396, Lvzhou Ring Road, Minhang District, Shanghai, PRC

(86)21-68582660-2792

globalsales@pjmzd.com

Work hours: 9:00-17:00